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Philips Respironics proves again that advanced thinking can lead to simpler solutions. BiPAP autoSV Advanced blends sophisticated, clinically-proven technologies to help make even the most complicated sleep apnea cases easier to manage and treatment more effective than previously possible. Updated algorithms, enhanced by auto EPAP, continually monitor and adjust to changing patient therapy needs, while proven Bi-Flex technology enhances patient comfort for proven long-term efficacy. Complex challenges simplified; that’s the advantage of BiPAP autoSV Advanced.In addition to the revolutionary algorithm, the BiPAP autoSV Advanced sleep therapy system also offers other proven Respironics technologies such as optional integrated heated humidification and built-in digital data storage using Respironics Encore SmartCard and Encore Pro Data Management Software.Developed for your most Patients with Complex Sleep Apnea

Complex Sleep Apnea occurs when a patient being treated for Obstructive Sleep Apnea develops Central Sleep Apnea when Continuous Positive Airway Pressure (CPAP) is administered.

Heart failure patients with Cheyne-Stokes Respiration

Often, heart failure patients display sleep-disordered breathing in the form of Cheyne-Stokes Respiration (CSR) – a periodic breathing disorder characterized by an alternating pattern of waxing and waning tidal volumes during periods of central apnea or hypopnea along with deep, rapid breathing (hyperventilation).

Obstructive Sleep Apnea (OSA):
OSA is the absence of airflow due to an occlusion in the upper airway that lasts at least 10 seconds in spite of continual effort to breathe. Severity is measured by the Apnea/Hypopnea Index (AHI) – the number of episodes per hour of sleep Central Sleep Apnea
Central Sleep Apnea is a pattern of breathing characterized by a normal deep inspiratory cycle interchanged with complete cessation of breathing. It is typically caused by problems with how the brain controls breathing rather than an occlusion of the airway. Complex Sleep Apnea
Complex sleep apnea is a condition that occurs when a patient is identified as having OSA, but with the application of Continuous Positive Airway Pressure (CPAP) to eliminate the OSA, the patient develops Central Sleep Apnea. The cause of complex sleep apnea is not known at this time. Periodic Breathing
Periodic breathing is defined as alternating periods of hyperventilation with waxing/waning tidal volume and periods of central hypopneas or apneas. There are many forms of periodic breathing, one of which is Cheyne-Stokes Respiration (CSR). CSR is characterized by a cyclic pattern of waxing and waning during periods of apnea, and deep, rapid breathing.


BiPAP autoSV Advanced


Obstructive component

Complex cases of sleep-disordered breathing present with varying degrees of obstructive versus central components. Maintaining a patent airway is vital, but oftentimes very difficult, making for particularly challenging titrations Solution.


          * Automatically distinguishes between obstructed and clear airway apneas
          * Increases EPAP only when necessary to maintain a patent airway
          * Automatic adjustment of EPAP simplifies titration and achieves proven efficacy at the minimum pressure levels
          * Adapts pressure to your patients’ needs as their conditions change (e.g., weight, alcohol use, lifestyle)

Central component

In the presence of central apneas, it is important for the patient to receive sufficient ventilation while still allowing natural pauses in breathing. Care must be taken not to over- or under- ventilate a patient with central apnea.

Advanced back-up rate

          * Timing of the back-up breath delivery is calculated to encourage spontaneous breathing at the patient’s own natural rate as necessary
          * Clinically-proven technology assures therapy is highly synchronous with the patient’s spontaneous breathing
          * Delivery of automatically calculated back-up breaths has been shown to be effective on a wide variety of complicated sleep-disordered breathing patients.

Unstable breathing

Patients with more complex sleep apnea conditions often demonstrate irregular and unstable breathing patterns. Standard CPAP or bi-level therapies were not designed to treat these patients.

Servo ventilation (SV) algorithm

          * Clinically-proven3 SV algorithm monitors peak flow and changes pressure support breath by breath to stabilize the breathing pattern
          * By establishing a targeted peak flow, the SV algorithm can rapidly normalize unstable breathing patterns with quick adjustments of pressure support

Patient comfort and compliance

Therapy is only effective if the patient uses it consistently. Unfortunately, exhaling against pressure can be very difficult for many patients.

Bi-Flex technology

          * Clinically-proven4 way to enhance patient comfort and compliance
          * Provides pressure relief during exhalation and at the critical transition points from exhalation to inhalation and back to exhalation
          * Makes it easier and more natural for those having difficulty adjusting or adhering to therapy

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